It looks like deputy ministers who were refusing to step down before running for the office that were stripped of may have seen the "wisdom" of the Prime Minister's request. Apparently there were more than two involved. At least two have already stepped down, and one is expected to step down in the next few days.
I think that the Prime Minister is having a pretty good week. He agrees to go forward with the Bout extradition and now he enforces at least the appearance of propriety in the upcoming by-elections.